Research Studies
PEEPS Study
The UNC Center for Women’s Mood Disorders wants to learn more about mood and brain function during the menopause transition. During this big life change, many women feel and behave differently because of the changes that are happening inside their bodies. We want to find ways to help women feel better during this time. We also want to help them understand the reasons for the change in emotions and different thoughts they might be having. This research study will look at a patch that is already FDA approved for improving bone density and managing hot flashes (called Climara) to see if it can also improve thoughts, feelings, and the ability to focus in women who are going through this change.
This study involves 6 visits, up to 4 of these can be done virtually on Zoom and 2 of these will be done at UNC. We will ask you to take a form of estrogen for three weeks, sit for 2 to 4 scans of your brain, and speak regularly with our study team about your thoughts and feelings. Before starting any medication, you would answer questions about your mood and health, and receive a physical exam.
You may be eligible to participate in this study if you are between the ages 44-55, have cycles more than 7 days earlier or later than usual, but you’ve still had a period in the last year, and are feeling less interested in your usual activities.
Study Screening Form: www.PEEPstudy.com
For additional questions, please contact the study coordinator: Kate Gibson (kathryn_gibson@med.unc.edu) or 919-966-5243
This research has been approved by the UNC Chapel Hill Biomedical IRB on December 16, 2021 (PI: Dichter, #21-2230). For questions on your rights as a research participant, please contact the UNC IRB at (919) 966-3113.
The EnDO CRU was established as part of legislative action to develop a diabetes treatment and research program at UNC in 1994
The EnDO CRU includes 7 investigators, 6 coordinators, 3 research assistants, administrative staff conducting 18 active studies with 8 in start-up
Impact:
·Participated in over 300 human studies
·Foundational in modern diabetes and obesity management.
·Published nearly 1000 manuscripts
·Secured over $100M in grants and contracts
·Supports other clinical research groups, basic scientists, and population research efforts.
INTERESTED IN OUR CLINICAL TRIALS?
Learn more about participating in clinical research at the Endocrinology, Diabetes, and Obesity Clinical Research Unit!
Visit researchforme.unc.edu or scan the QR code to go directly to our recruiting trials.
